Case Study
César Bimbi
Ausbruch einer durch Katzen übertragenen Sporotrichose im südlichen Brasilien: Konsequenzen für humane Ansteckung
Outbreak of Feline Sporotrichosis in the Southern Region of Brazil: Implications for Human Infection
(NACH CARE-LEITLINIE)
Keywords | Summary | Correspondence | Literature
Keywords
emerging zoonoses, feline sporotrichosis, neglected diseases, Sporothrix brasiliensis, Sporotrichosis
Schlüsselworte
feline Sporotrichose, neu auftauchende Zoonosen, Sporothrix brasiliensis, Sporotrichose, vernachlässigte Erkrankungen
Summary
Sporotrichosis, a neglected zoonotic subcutaneous mycosis, emerges as a major public health challenge in South America, with Brazil leading the ranking as the most endemic country for this disease worldwide. The actual uncontrolled spread of the disease is based on the greater virulence and adaptation of the species Sporothrix brasiliensis to felines. In this context, we report four human cases of primary cutaneous sporotrichosis, highlighting the connection between infection in cats and its transmission to humans.
Zusammenfassung
Die Sporotrichose ist eine vernachlässigte vom Tier auf den Menschen übertragbare subkutane Mykose. Die entwickelt sich zu einem wichtigen Problem der öffentlichen Gesundheit in Südamerika. Brasilien hat weltweit die höchste Inzidenz. Die derzeit unkontrollierte Ausbreitung der Erkrankung ist auf die größere Virulenz und die Anpassung der Spezies Sporothrix brasiliensis an Katzen zurückzuführen. In diesem Zusammenhang berichten wir über vier humane Fälle einer primär kutanen Sporotrichose und verweisen auf die Assoziation infizierter Katzen zur humanen Infektion.
Leider haben Sie sich nicht eingeloggt, um den Beitrag lesen zu können. Bitte loggen Sie sich ein oder beantragen Sie Ihre Zugangsberechtigung. Vielen Dank. Weitere Informationen finden Sie hier>
Korrespondenz-Adresse
César Bimbi, MD
Private Clinic, Dermatologia Médica & Laser
R. 24 de Outubro, 111 - Sala 502
Moinhos de Vento
Porto Alegre, RS
BR-90510-002
cbimbi@terra.com.br
Konklusion
The purpose of this exposition is to highlight the ongoing outbreak of sporotrichosis in Brazil, pointing to a situation of public calamity. Until 2007, only S. schenckii was recognized as the etiological agent of sporotrichosis, but this scenario has recently changed, with species recovered from cat lesions identified as S. brasiliensis in 96.5% of cases [7]. In a recent genomic epidemiology study 85% of isolates were S. brasiliensis, and all were reported from Brazil, and 14% were S. schenckii [4]. Awareness and implementation of effective measures are essential to contain the ongoing outbreak of sporotrichosis and mitigate its impact on public health.
Literatur
1. Lopes-Bezerra LM, Mora-Montes HM, Zhang Y, Nino-Vega G, Rodrigues AM, de Camargo ZP, de Hoog S. Sporotrichosis between 1898 and 2017: The evolution of knowledge on a changeable disease and on emerging etiological agents. Med Mycol. 2018;56(Suppl 1):126-143.
2. Gremião IDF, Martins da Silva da Rocha E, Montenegro H, Carneiro AJB, Xavier MO, de Farias MR, Monti F, Mansho W, de Macedo Assunção Pereira RH, Pereira SA, Lopes-Bezerra LM. Guideline for the management of feline sporotrichosis caused by Sporothrix brasiliensis and literature revision. Braz J Microbiol. 2021;52(1):107-124.
3. Gremião ID, Menezes RC, Schubach TM, Figueiredo AB, Cavalcanti MC, Pereira SA. Feline sporotrichosis: epidemiological and clinical aspects. Med Mycol. 2015;53(1):15-21.
4. Ribeiro Dos Santos A, Misas E, Min B, Le N, Bagal UR, Parnell LA, Sexton DJ, Lockhart SR, de Souza Carvalho Melhem M, Takahashi JPF, Oliboni GM, Bonfieti LX, Cappellano P, Sampaio JLM, Araujo LS, Alves Filho HL, Venturini J, Chiller TM, Litvintseva AP, Chow NA. Emergence of zoonotic sporotrichosis in Brazil: a genomic epidemiology study. Lancet Microbe. 2024;5(3):e282-e290.
5. Gómez-Gaviria M, Martínez-Álvarez JA, Mora-Montes HM. Current progress in Sporothrix brasiliensis basic aspects. J Fungi (Basel). 2023;9(5):533.
6. Queiroz-Telles F, Bonifaz A. Implantation mycoses. An unsolved problem. Med Mycol
7. Almeida-Paes R, de Oliveira MM, Freitas DF, do Valle AC, Zancopé-Oliveira RM, Gutierrez-Galhardo MC. Sporotrichosis in Rio de Janeiro, Brazil: Sporothrix brasiliensis is associated with atypical clinical presentations. PLoS Negl Trop Dis. 2014;8(9):e3094.
8. Thomson P, González C, Blank O, Ramírez V, Río CD, Santibáñez S, Pena P. Sporotrichosis outbreak due to Sporothrix brasiliensis in domestic cats in Magallanes, Chile: A one-health-approach study. J Fungi (Basel). 2023;9(2):226.
9. Han HS, Kano R. Feline sporotrichosis in Asia. Braz J Microbiol. 2021;52(1):125-134.
10. Barile F, Mastrolonardo M, Loconsole F, Rantuccio F. Cutaneous sporotrichosis in the period 1978-1992 in the province of Bari, Apulia, Southern Italy. Mycoses. 1993;36(5-6):181-185.
